Detail publikace

Specification and simplified analyzing data from MS/MS spectrometry

VALLA, M. PLCHÚT, M. PROVAZNÍK, I.

Originální název

Specification and simplified analyzing data from MS/MS spectrometry

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

The goal of this work was to design a suitable method for unifying score values from various identification tools of proteins identification in tandem mass spectrometry into a single score value. Output data from the mass spectrometric method were processed by two independent search tools Mascot and X!Tandem. Those were selected especially for their wide applications in proteomic laboratories. Results of both methods were evaluated through a newly designed function and unified to a single valued score that clearly identifies found proteins. The newly designed function of producing of scored values was termed Metascore and implemented into MATLAB computational environment. Given results were successfully tested on selected real data available in public databases of proteomic sequences

Klíčová slova

Score, Mascot, X!Tandem, Metascore, MS/MS, peptide mass fingerprint, tandem mass spectrometry, MS/MS, spectrometry

Autoři

VALLA, M.; PLCHÚT, M.; PROVAZNÍK, I.

Rok RIV

2009

Vydáno

7. 9. 2009

Nakladatel

IFMBE

ISBN

978-3-642-03881-5

Kniha

Proc. World Congress of Medical Physics and Biomedical Engineering

Strany od

1510

Strany do

1512

Strany počet

3

URL

BibTex

@inproceedings{BUT31402,
  author="Martin {Valla} and Martin {Plchút} and Valentine {Provazník}",
  title="Specification and simplified analyzing data from MS/MS spectrometry",
  booktitle="Proc. World Congress of Medical Physics and Biomedical Engineering",
  year="2009",
  pages="1510--1512",
  publisher="IFMBE",
  isbn="978-3-642-03881-5",
  url="http://conference.vde.com/world-congress-2009/Pages/Home.aspx"
}