Detail publikace

Suggestion of electrochemical sensors for microanalysis of content of copper in biological samples

HUBÁLEK, J. DUŠA, F. FABRIK, I. HÚSKA, D. KIZEK, R. JELEN, F. TRNKOVÁ, L.

Originální název

Suggestion of electrochemical sensors for microanalysis of content of copper in biological samples

Typ

článek v časopise - ostatní, Jost

Jazyk

angličtina

Originální abstrakt

There have been published several papers on voltammetric ultra-trace determination of some nucleic bases in the presence of Cu(II) using a mercury electrode or solid amalgam electrodes. Carbon electrodes can be used for the same purposes. The aim of this work was to employ the behaviour of purines in the presence of Cu(II) to determine these metal ions. Primarily we aimed on investigation of basic electrochemical behaviour of detection copper at hanging mercury drop and carbon paste electrodes by using of cyclic and differential pulse voltammetry. Thanks to formation of the complex adenine-Cu(II) under the specific conditions the peak of this complex was measured at -0.6 V. The detection limit (3 S/N) for Cu(II) ions was estimated as 5 nM. By using of this approach we were able to determine the content of copper in animal tissues even at tens of nM. Moreover we utilized suggested approach to monitor the level of copper ions in samples of blood serum of patients with metabolic disorder.

Klíčová slova

copper detection, electrochemical sensor, carbon electrode

Autoři

HUBÁLEK, J.; DUŠA, F.; FABRIK, I.; HÚSKA, D.; KIZEK, R.; JELEN, F.; TRNKOVÁ, L.

Rok RIV

2008

Vydáno

26. 10. 2008

Nakladatel

IEEE

Místo

Lecce, Itálie

ISSN

1930-0395

Periodikum

The Seventh IEEE Conference on SENSORS

Ročník

2008

Číslo

7

Stát

Spojené státy americké

Strany od

902

Strany do

905

Strany počet

4

BibTex

@article{BUT49157,
  author="HUBÁLEK, J. and DUŠA, F. and FABRIK, I. and HÚSKA, D. and KIZEK, R. and JELEN, F. and TRNKOVÁ, L.",
  title="Suggestion of electrochemical sensors for microanalysis of content of copper in biological samples",
  journal="The Seventh IEEE Conference on SENSORS",
  year="2008",
  volume="2008",
  number="7",
  pages="902--905",
  issn="1930-0395"
}