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LAEMMER, R. KOLÁŘ, R. JAN, J. MARDIN, C.
Originální název
Impact Of Parapapillary Autofluorescence In Glaucoma: Clinical Aspects
Anglický název
Typ
článek v časopise - ostatní, Jost
Jazyk
čeština
Originální abstrakt
Parapapillary atrophy is an important clinical sign associated with progressive optic disc damage and visual field loss in patients with glaucoma. Histologic and spectroscopic results revealed an accumulation of lipofuscin as the dominant fundus fluorophore localized in the lysosomes of the retinal pigmentepithelium in the parapapillary atrophic zone. We investigated morphologic characteristics of parapapillary autofluorescence in patients with different entities and stages of glaucoma compared to healthy controls using Scanning Laser Ophthalmoscopy. Autofluorescence was measured with HRA standard software and compared to a new semiautomatic approach. Both, area and mean distance of the autofluorescence regions from the optic disc border were well associated with increasing glaucomatous damage. Changes were more pronounced for early stages. Semiautomatic segmentation improved interobserver variability.
Anglický abstrakt
Klíčová slova
glaucoma, retinal imaging, autofluorescence
Klíčová slova v angličtině
Autoři
LAEMMER, R.; KOLÁŘ, R.; JAN, J.; MARDIN, C.
Rok RIV
2008
Vydáno
27. 6. 2008
ISSN
1211-412X
Periodikum
Analysis of Biomedical Signals and Images
Ročník
19
Číslo
1
Stát
Česká republika
Strany od
Strany do
4
Strany počet
URL
https://ipac.svkkl.cz/arl-kl/cs/detail-kl_us_cat-1441077-Analysis-of-biomedical-signals-and-images/
BibTex
@article{BUT49681, author="Radim {Kolář} and Robert {Laemmer} and Jiří {Jan} and Christian Y {Mardin}", title="Impact Of Parapapillary Autofluorescence In Glaucoma: Clinical Aspects", journal="Analysis of Biomedical Signals and Images", year="2008", volume="19", number="1", pages="1--4", issn="1211-412X", url="https://ipac.svkkl.cz/arl-kl/cs/detail-kl_us_cat-1441077-Analysis-of-biomedical-signals-and-images/" }