Detail publikace

Clustering Techniques for Protein Fragments Analysis

BURGETOVÁ, I. ZENDULKA, J. LEXA, M.

Originální název

Clustering Techniques for Protein Fragments Analysis

Typ

kniha odborná

Jazyk

angličtina

Originální abstrakt

This book presents a novel method for clustering of protein substructures that we developed in order to study the relationships between protein sequences and their structure. We show some properties of this method and the experimental results obtained by analyzing real data from PDB (Protein Data Bank). Furthermore, we present the results of the comparison of our method and the most commonly used methods for clustering of protein structures. The main advantage of our method is its high efficiency and scalability, which are key factors for analyzing large data sets. Finally, we propose a procedure for finding sequence profiles that tend to occur in more than one structural conformation but the number of their structural conformations is limited. This procedure is based on our method for protein substructure clustering.

Klíčová slova

Protein structure, Protein Data Bank, clustering, density-based clustering, sequence-structure relationships in proteins, clustering of protein fragments, protein structure prediction, sequence-structures fragments search.

Autoři

BURGETOVÁ, I.; ZENDULKA, J.; LEXA, M.

Rok RIV

2010

Vydáno

31. 12. 2010

Nakladatel

Faculty of Information Technology BUT

Místo

Brno

ISBN

978-80-214-4207-8

Strany počet

102

BibTex

@book{BUT62045,
  author="Ivana {Burgetová} and Jaroslav {Zendulka} and Matej {Lexa}",
  title="Clustering Techniques for Protein Fragments Analysis",
  year="2010",
  publisher="Faculty of Information Technology BUT",
  address="Brno",
  pages="102",
  isbn="978-80-214-4207-8"
}