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KREJČOVÁ, L. FABRIK, I. HYNEK, D. KŘÍŽKOVÁ, S. GUMULEC, J. VACULOVIČOVÁ, M. ADAM, V. BABULA, P. TRNKOVÁ, L. STIBOROVÁ, M. HUBÁLEK, J. MASAŘÍK, M. BINKOVÁ, H. ECKSCHLAGER, T. KIZEK, R.
Originální název
Metallothionein Electrochemically Determined using Brdicka Reaction as a Promising Blood Marker of Head and Neck Malignant Tumours
Typ
článek v časopise ve Web of Science, Jimp
Jazyk
angličtina
Originální abstrakt
There are more than half of million patients who fall ill with head and neck carcinoma per year, which 6 % of annually newly diagnosed malignant diseases in the world. The most important objective of this study is the electrochemical monitoring of metallothionein levels in patients with primary malignant tumors in head and neck examination and the suitability of electrochemical detection as a technique used in clinical practice. In conclusion, MT levels are closely associated with the rate of tumour differentiation, stage of tumour disease and tumour cell characteristics. Our study demonstrates not only changes in blood MT levels in patients suffering from malignant tumour disease in head and neck area, but also suitability of electrochemical techniques for blood analysis.
Klíčová slova
electrochemical detection; head and neck cancer; voltammetry; catalytic signal; metallothionein; marker
Autoři
KREJČOVÁ, L.; FABRIK, I.; HYNEK, D.; KŘÍŽKOVÁ, S.; GUMULEC, J.; VACULOVIČOVÁ, M.; ADAM, V.; BABULA, P.; TRNKOVÁ, L.; STIBOROVÁ, M.; HUBÁLEK, J.; MASAŘÍK, M.; BINKOVÁ, H.; ECKSCHLAGER, T.; KIZEK, R.
Rok RIV
2012
Vydáno
1. 3. 2012
ISSN
1452-3981
Periodikum
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
Ročník
7
Číslo
3
Stát
Srbská republika
Strany od
1767
Strany do
1784
Strany počet
18
BibTex
@article{BUT90342, author="Ludmila {Krejčová} and Ivo {Fabrik} and David {Hynek} and Soňa {Křížková} and Jaromír {Gumulec} and Markéta {Vaculovičová} and Vojtěch {Adam} and Petr {Babula} and Libuše {Trnková} and Marie {Stiborová} and Jaromír {Hubálek} and Michal {Masařík} and Hana {Binková} and Tomáš {Eckschlager} and René {Kizek}", title="Metallothionein Electrochemically Determined using Brdicka Reaction as a Promising Blood Marker of Head and Neck Malignant Tumours", journal="INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE", year="2012", volume="7", number="3", pages="1767--1784", issn="1452-3981" }