Project detail

Closed-loop Individualized image-guided Transcranial Ultrasonic Stimulation

Duration: 01.08.2022 — 31.07.2026

Funding resources

Evropská unie - HORIZON EUROPE

- whole funder (2022-08-01 - 2026-07-31)

On the project

We are joining forces across Europe to advance a new non-invasive technology - transcranial ultrasound stimulation (TUS) - to reversibly modulate brain regions with exquisite millimetre precision, even deep in the brain. As such, we aim to establish an urgently needed novel treatment option for neurological and psychiatric diseases. TUS combines the precision and reach of invasive deep brain stimulation, required to directly target clinically relevant structures, with the non-invasive and low-cost nature of transcranial electromagnetic techniques that are inherently limited in focus and depth.

Description in Czech
Spojujeme síly po celé Evropě, abychom pokročili v nové neinvazivní technologii - transkraniální ultrazvukové stimulaci (TUS) - k reverzibilní modulaci oblastí mozku s vynikající milimetrovou přesností, a to i hluboko v mozku. Jako takové se snažíme vytvořit naléhavě potřebnou novou možnost léčby neurologických a psychiatrických onemocnění. TUS kombinuje přesnost a dosah invazivní hluboké mozkové stimulace, potřebné k přímému zacílení na klinicky relevantní struktury, s neinvazivní a nízkonákladovou povahou transkraniálních elektromagnetických technik, které jsou ze své podstaty omezené v ohnisku a hloubce.

Keywords
transcranial ultrasound stimulation, human brain, magnetic resonance imaging

Mark

101071008

Default language

English

People responsible

Bayer David, Ing. - fellow researcher
Chlebík Jakub, Ing. - fellow researcher
Jaroš Marta, Ing., Ph.D. - fellow researcher
Kupčo Patrik, Bc. - fellow researcher
Olšák Ondřej, Ing. - fellow researcher
Jaroš Jiří, doc. Ing., Ph.D. - principal person responsible

Units

Department of Computer Systems
- co-beneficiary (2021-10-26 - 2026-07-31)
University College London
- beneficiary (2021-10-26 - 2026-07-31)

Results

OLŠÁK, O.; JAROŠ, J. Evaluation of libraries for the one-dimensional sparse Fourier transform. Ostrava: 2022. p. 0-0.
Detail

OLŠÁK, O.; JAROŠ, J. On the usage of the Sparse Fourier Transform in ultrasound propagation simulation. In ICBRA '23: Proceedings of the 10th International Conference on Bioinformatics Research and Applications. New York: Association for Computing Machinery, 2024. p. 107-113. ISBN: 979-8-4007-0815-2.
Detail

OLŠÁK, O.; JAROŠ, J. Techniques for Efficient Fourier Transform Computation in Ultrasound Simulations. Soláň: 2024. p. 0-0.
Detail

OLŠÁK, O.; JAROŠ, M.; JAROŠ, J. System for managing HPC-services and workflow executions. Ostrava: 2023. p. 0-0.
Detail

JAROŠ, J.; JAROŠ, M.; BUCHTA, M. Estimation of Distributed Ultrasound Simulation Execution Time Using Machine Learning. In 2024 IEEE Congress on Evolutionary Computation (CEC). Yokohama: Institute of Electrical and Electronics Engineers, 2024. p. 1-8. ISBN: 979-8-3503-0836-5.
Detail

BAYER, D.; JAROŠ, J. Acceleration of Heat Diffusion Simulation on Single-Node Systems. Ostrava: 2023. p. 0-0.
Detail

OLŠÁK, O.; JAROŠ, J. Techniques for Efficient Fourier Transform Computation in Ultrasound Simulations. HPDC '24: Proceedings of the 33nd International Symposium on High-Performance Parallel and Distributed Computing. New York: Association for Computing Machinery, 2024. p. 361-363. ISBN: 979-8-4007-0413-0.
Detail

JAROŠ, M.; JAROŠ, J. k-Dispatch: Enabling Cost-Optimized Biomedical Workflow Offloading. HPDC '24: Proceedings of the 33rd International Symposium on High-Performance Parallel and Distributed Computing. New York: Association for Computing Machinery, 2024. p. 358-360. ISBN: 979-8-4007-0413-0.
Detail

JAROŠ, J.; DUCHOŇ, R. Acceleration of Ultrasound Neurostimulation Using Mixed-Precision Arithmetic. HPDC '24: Proceedings of the 33rd International Symposium on High-Performance Parallel and Distributed Computing. New York: Association for Computing Machinery, 2024. p. 370-372. ISBN: 979-8-4007-0413-0.
Detail

JAROŠ, J.: MPI Error Checker; Software Package for Reporting Errors in Distributed MPI Applications. https://github.com/jarosjir/MPIErrorChecker. URL: https://github.com/jarosjir/MPIErrorChecker. (software)
Detail

Responsibility: Jaroš Jiří, doc. Ing., Ph.D.