Project detail

Smart Theranostic Liposomal Nanovehicles for Cancer Silencing

Duration: 01.03.2022 — 28.02.2023

Funding resources

Brno University of Technology - Vnitřní projekty VUT

- whole funder (2022-01-01 - 2023-12-31)

On the project

The project deals with theranostic nanoparticles based on liposomal siRNA-complex (lipoplex), which can handle requirements on a successful anticancer drug nanoformulation. Lipoplexes are made by injection method to form bilayer particles, and therapeutic siRNA is inserted into the lipoplex core by electrostatic interactions. Lipoplexes will combine unique gene silencing therapy properties with diagnostic capabilities mediated by gadolinium-based contrast agents. These multiunctional nanoparticles will pave new avenues for cancer theranostics.

Mark

CEITEC VUT-J-22-7814

Default language

Czech

People responsible

Heger Zbyněk, doc. - fellow researcher
Vojníková Michaela, Ing. - principal person responsible

Units

Central European Institute of Technology BUT
- beneficiary (2022-01-01 - 2022-12-31)
Smart Nanodevices
- co-beneficiary (2022-03-01 - 2023-02-28)

Results

MARÁKOVÁ, E.; VOJNÍKOVÁ, M.; MILLER, A.; GRUBEROVÁ, E.; HEGER, Z. Advanced Lipid-Based Nanotransporters for Encapsulation of Cytochrome C. In Proceedings of the 9th World Congress on Recent Advances in Nanotechnology. London: INTERNATIONAL ASET INC. – ALL, 2024. ISBN: 9781990800337.
Detail

Responsibility: Vojníková Michaela, Ing.