Project detail

3D cell culture of human osteoblasts and osteosarcoma cells in a bioengineered bone marrow model

Duration: 01.03.2024 — 28.02.2025

Funding resources

Brno University of Technology - Vnitřní projekty VUT

- whole funder (2024-01-01 - 2025-12-31)

On the project

This project focuses on the development of the novel bone marrow model using scaffold/hydrogel structures as a platform for 3D cell culture of human osteoblasts and osteosarcoma cells. The aim of this project is to investigate molecular and cellular mechanisms in the newly developed model. The utilization of this model and the understanding of the cell behavior will contribute to the advancement of targeted therapies for various bone marrow-related disorders.

Mark

CEITEC VUT-J-24-8642

Default language

Czech

People responsible

Montufar Jimenez Edgar Benjamin, M.Sc., Ph.D. - fellow researcher
Drotárová Lenka, Ing. - principal person responsible

Units

Advanced Coatings
- beneficiary (2024-01-01 - 2024-12-31)
Central European Institute of Technology BUT
- responsible department (2024-01-31 - 2024-03-04)

Results

DROTÁROVÁ, L.; SLÁMEČKA, K.; BALINT, M.; REMEŠOVÁ, M.; HUDÁK, R.; ŽIVČÁK, J.; ČELKO, L.; MONTUFAR JIMENEZ, E. Biodegradable WE43 Mg alloy/hydroxyapatite interpenetrating phase composites with reduced hydrogen evolution. Bioactive Materials, 2024, vol. 42, no. 12, p. 519-530. ISSN: 2452-199X.
Detail

Responsibility: Drotárová Lenka, Ing.