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RUTTKAY-NEDECKÝ, B. JIMENEZ JIMENEZ, A. NEJDL, L. CHUDOBOVÁ, D. GUMULEC, J. MASAŘÍK, M. ADAM, V. KIZEK, R.
Original Title
Relevance of infection with human papillomavirus: The role of the p53 tumor suppressor protein and E6/E7 zinc finger proteins
Type
journal article in Web of Science
Language
English
Original Abstract
Human papillomaviruses (HPV) are small circular, double-stranded DNA viruses infecting epithelial tissues. HPV types can be classified both as high-risk or low-risk. Of the more than 120 different identified types of HPV, the majority are involved in infections of the genital tract, cancer of the cervix, vulva, vagina and penis, and of non-anogenital localizations, such as the head and neck areas. From the point of view of the infection, human papillomaviruses have developed several molecular mechanisms to enable infected cells to suppress apoptosis. This review provides a comprehensive and critical summary of the current literature that focuses on cervical carcinoma and cancer of the head and neck caused by HPV
Keywords
papillomaviruses, cancer of the cervix, infection, molecular mechanisms
Authors
RUTTKAY-NEDECKÝ, B.; JIMENEZ JIMENEZ, A.; NEJDL, L.; CHUDOBOVÁ, D.; GUMULEC, J.; MASAŘÍK, M.; ADAM, V.; KIZEK, R.
RIV year
2013
Released
1. 12. 2013
ISBN
1019-6439
Periodical
INTERNATIONAL JOURNAL OF ONCOLOGY
Year of study
43
Number
6
State
Hellenic Republic
Pages from
1754
Pages to
1762
Pages count
9
BibTex
@article{BUT101244, author="Branislav {Ruttkay-Nedecký} and Ana Maria {Jimenez Jimenez} and Lukáš {Nejdl} and Dagmar {Hegerová} and Jaromír {Gumulec} and Michal {Masařík} and Vojtěch {Adam} and René {Kizek}", title="Relevance of infection with human papillomavirus: The role of the p53 tumor suppressor protein and E6/E7 zinc finger proteins", journal="INTERNATIONAL JOURNAL OF ONCOLOGY", year="2013", volume="43", number="6", pages="1754--1762", doi="10.3892/ijo.2013.2105", issn="1019-6439" }