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Detail publikace
RUTTKAY-NEDECKÝ, B. JIMENEZ JIMENEZ, A. NEJDL, L. CHUDOBOVÁ, D. GUMULEC, J. MASAŘÍK, M. ADAM, V. KIZEK, R.
Originální název
Relevance of infection with human papillomavirus: The role of the p53 tumor suppressor protein and E6/E7 zinc finger proteins
Typ
článek v časopise ve Web of Science, Jimp
Jazyk
angličtina
Originální abstrakt
Human papillomaviruses (HPV) are small circular, double-stranded DNA viruses infecting epithelial tissues. HPV types can be classified both as high-risk or low-risk. Of the more than 120 different identified types of HPV, the majority are involved in infections of the genital tract, cancer of the cervix, vulva, vagina and penis, and of non-anogenital localizations, such as the head and neck areas. From the point of view of the infection, human papillomaviruses have developed several molecular mechanisms to enable infected cells to suppress apoptosis. This review provides a comprehensive and critical summary of the current literature that focuses on cervical carcinoma and cancer of the head and neck caused by HPV
Klíčová slova
papillomaviruses, cancer of the cervix, infection, molecular mechanisms
Autoři
RUTTKAY-NEDECKÝ, B.; JIMENEZ JIMENEZ, A.; NEJDL, L.; CHUDOBOVÁ, D.; GUMULEC, J.; MASAŘÍK, M.; ADAM, V.; KIZEK, R.
Rok RIV
2013
Vydáno
1. 12. 2013
ISSN
1019-6439
Periodikum
INTERNATIONAL JOURNAL OF ONCOLOGY
Ročník
43
Číslo
6
Stát
Řecká republika
Strany od
1754
Strany do
1762
Strany počet
9
BibTex
@article{BUT101244, author="Branislav {Ruttkay-Nedecký} and Ana Maria {Jimenez Jimenez} and Lukáš {Nejdl} and Dagmar {Hegerová} and Jaromír {Gumulec} and Michal {Masařík} and Vojtěch {Adam} and René {Kizek}", title="Relevance of infection with human papillomavirus: The role of the p53 tumor suppressor protein and E6/E7 zinc finger proteins", journal="INTERNATIONAL JOURNAL OF ONCOLOGY", year="2013", volume="43", number="6", pages="1754--1762", doi="10.3892/ijo.2013.2105", issn="1019-6439" }