Detail publikace

Relevance of infection with human papillomavirus: The role of the p53 tumor suppressor protein and E6/E7 zinc finger proteins

RUTTKAY-NEDECKÝ, B. JIMENEZ JIMENEZ, A. NEJDL, L. CHUDOBOVÁ, D. GUMULEC, J. MASAŘÍK, M. ADAM, V. KIZEK, R.

Originální název

Relevance of infection with human papillomavirus: The role of the p53 tumor suppressor protein and E6/E7 zinc finger proteins

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Human papillomaviruses (HPV) are small circular, double-stranded DNA viruses infecting epithelial tissues. HPV types can be classified both as high-risk or low-risk. Of the more than 120 different identified types of HPV, the majority are involved in infections of the genital tract, cancer of the cervix, vulva, vagina and penis, and of non-anogenital localizations, such as the head and neck areas. From the point of view of the infection, human papillomaviruses have developed several molecular mechanisms to enable infected cells to suppress apoptosis. This review provides a comprehensive and critical summary of the current literature that focuses on cervical carcinoma and cancer of the head and neck caused by HPV

Klíčová slova

papillomaviruses, cancer of the cervix, infection, molecular mechanisms

Autoři

RUTTKAY-NEDECKÝ, B.; JIMENEZ JIMENEZ, A.; NEJDL, L.; CHUDOBOVÁ, D.; GUMULEC, J.; MASAŘÍK, M.; ADAM, V.; KIZEK, R.

Rok RIV

2013

Vydáno

1. 12. 2013

ISSN

1019-6439

Periodikum

INTERNATIONAL JOURNAL OF ONCOLOGY

Ročník

43

Číslo

6

Stát

Řecká republika

Strany od

1754

Strany do

1762

Strany počet

9

BibTex

@article{BUT101244,
  author="Branislav {Ruttkay-Nedecký} and Ana Maria {Jimenez Jimenez} and Lukáš {Nejdl} and Dagmar {Hegerová} and Jaromír {Gumulec} and Michal {Masařík} and Vojtěch {Adam} and René {Kizek}",
  title="Relevance of infection with human papillomavirus: The role of the p53 tumor suppressor protein and E6/E7 zinc finger proteins",
  journal="INTERNATIONAL JOURNAL OF ONCOLOGY",
  year="2013",
  volume="43",
  number="6",
  pages="1754--1762",
  doi="10.3892/ijo.2013.2105",
  issn="1019-6439"
}