Product detail

PredictSNP: Robust and Accurate Consensus Classifier for Prediction of Disease-Related Mutations

BENDL, J. ŠTOURAČ, J. ŠALANDA, O. PAVELKA, A. WIEBEN, E. ZENDULKA, J. BREZOVSKÝ, J. DAMBORSKÝ, J.

Product type

software

Abstract

This tool estimates the effect of amino acid substitutions on protein function. The predictions are based on the results of the existing tools MAPP, PhD-SNP, PolyPhen-1, PolyPhen-2, SIFT and SNAP. The principle of consensual approach is described in: "Bendl et. al. (2014) PredictSNP: Robust and Accurate Consensus Classifier for Prediction of Disease-Related Mutations. PLoS Computational Biology, 10.". The user interface shows not only the overall results and the results of underlying tools but also the experimental annotations extracted from PMD and Uniprot databases.

Keywords

SNP, single nucleotide polymorphism, SNV, single nucleotide variant, pathogenicity prediction, disease-related mutations

Create date

1. 7. 2013

Location

http://loschmidt.chemi.muni.cz/predictsnp/

Possibilities of use

Využití výsledku jiným subjektem je v některých případech možné bez nabytí licence

Licence fee

Poskytovatel licence na výsledek nepožaduje licenční poplatek

www

http://loschmidt.chemi.muni.cz/predictsnp/

Documents

predictsnp-1.0.tar.gz