Detail produktu

PredictSNP: Robust and Accurate Consensus Classifier for Prediction of Disease-Related Mutations

BENDL, J. ŠTOURAČ, J. ŠALANDA, O. PAVELKA, A. WIEBEN, E. ZENDULKA, J. BREZOVSKÝ, J. DAMBORSKÝ, J.

Typ produktu

software

Abstrakt

This tool estimates the effect of amino acid substitutions on protein function. The predictions are based on the results of the existing tools MAPP, PhD-SNP, PolyPhen-1, PolyPhen-2, SIFT and SNAP. The principle of consensual approach is described in: "Bendl et. al. (2014) PredictSNP: Robust and Accurate Consensus Classifier for Prediction of Disease-Related Mutations. PLoS Computational Biology, 10.". The user interface shows not only the overall results and the results of underlying tools but also the experimental annotations extracted from PMD and Uniprot databases.

Klíčová slova

SNP, single nucleotide polymorphism, SNV, single nucleotide variant, pathogenicity prediction, disease-related mutations

Datum vzniku

1. 7. 2013

Umístění

http://loschmidt.chemi.muni.cz/predictsnp/

Možnosti využití

Využití výsledku jiným subjektem je v některých případech možné bez nabytí licence

Licenční poplatek

Poskytovatel licence na výsledek nepožaduje licenční poplatek

www

http://loschmidt.chemi.muni.cz/predictsnp/

Dokumenty

predictsnp-1.0.tar.gz