Publication detail

Nanotechnologies in protein microarrays

KŘÍŽKOVÁ, S. HEGER, Z. ZALEWSKA, M. MOULICK, A. ADAM, V. KIZEK, R.

Original Title

Nanotechnologies in protein microarrays

Type

journal article in Web of Science

Language

English

Original Abstract

Protein microarray technology became an important research tool for study and detection of proteins, protein-protein interactions and a number of other applications. The utilization of nanoparticle-based materials and nanotechnology-based techniques for immobilization allows us not only to extend the surface for biomolecule immobilization resulting in enhanced substrate binding properties, decreased background signals and enhanced reporter systems for more sensitive assays. Generally in contemporarily developed microarray systems, multiple nanotechnology-based techniques are combined. In this review, applications of nanoparticles and nanotechnologies in creating protein microarrays, proteins immobilization and detection are summarized. We anticipate that advanced nanotechnologies can be exploited to expand promising fields of proteins identification, monitoring of protein-protein or drug-protein interactions, or proteins structures.

Keywords

DAPA; nanomaterials; NAPPA; quantum dots; recognition element

Authors

KŘÍŽKOVÁ, S.; HEGER, Z.; ZALEWSKA, M.; MOULICK, A.; ADAM, V.; KIZEK, R.

Released

1. 1. 2015

ISBN

1743-5889

Periodical

Nanomedicine

Year of study

10

Number

17

State

United Kingdom of Great Britain and Northern Ireland

Pages from

2743

Pages to

2755

Pages count

13

BibTex

@article{BUT145216,
  author="Soňa {Křížková} and Zbyněk {Heger} and Marta Barbara {Zalewska} and Amitava {Moulick} and Vojtěch {Adam} and René {Kizek}",
  title="Nanotechnologies in protein microarrays",
  journal="Nanomedicine",
  year="2015",
  volume="10",
  number="17",
  pages="2743--2755",
  doi="10.2217/nnm.15.81",
  issn="1743-5889"
}