Detail publikace

Nanotechnologies in protein microarrays

KŘÍŽKOVÁ, S. HEGER, Z. ZALEWSKA, M. MOULICK, A. ADAM, V. KIZEK, R.

Originální název

Nanotechnologies in protein microarrays

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Protein microarray technology became an important research tool for study and detection of proteins, protein-protein interactions and a number of other applications. The utilization of nanoparticle-based materials and nanotechnology-based techniques for immobilization allows us not only to extend the surface for biomolecule immobilization resulting in enhanced substrate binding properties, decreased background signals and enhanced reporter systems for more sensitive assays. Generally in contemporarily developed microarray systems, multiple nanotechnology-based techniques are combined. In this review, applications of nanoparticles and nanotechnologies in creating protein microarrays, proteins immobilization and detection are summarized. We anticipate that advanced nanotechnologies can be exploited to expand promising fields of proteins identification, monitoring of protein-protein or drug-protein interactions, or proteins structures.

Klíčová slova

DAPA; nanomaterials; NAPPA; quantum dots; recognition element

Autoři

KŘÍŽKOVÁ, S.; HEGER, Z.; ZALEWSKA, M.; MOULICK, A.; ADAM, V.; KIZEK, R.

Vydáno

1. 1. 2015

ISSN

1743-5889

Periodikum

Nanomedicine

Ročník

10

Číslo

17

Stát

Spojené království Velké Británie a Severního Irska

Strany od

2743

Strany do

2755

Strany počet

13

BibTex

@article{BUT145216,
  author="Soňa {Křížková} and Zbyněk {Heger} and Marta Barbara {Zalewska} and Amitava {Moulick} and Vojtěch {Adam} and René {Kizek}",
  title="Nanotechnologies in protein microarrays",
  journal="Nanomedicine",
  year="2015",
  volume="10",
  number="17",
  pages="2743--2755",
  doi="10.2217/nnm.15.81",
  issn="1743-5889"
}