Publication detail

Miniaturized LC in Molecular Omics

AYDOFAN, C. RIGANO, F. KUJOVSKÁ KRČMOVÁ, L. CHUNG, DS. MACKA, M. MONDELLO, L.

Original Title

Miniaturized LC in Molecular Omics

Type

journal article in Web of Science

Language

English

Original Abstract

Miniaturized LC has evolved at an exponential rate over the last 50 years. In the past decade, it has received considerable attention in the field of bioanalytical separation science and technology due to the need to measure different classes of biomolecules present in a variety of matrixes on a global scale to gain a deeper understanding of complex biological processes. This field has become a dominant area underpinning the molecular omics research (e.g., proteomics, metabolomics, lipidomics, and foodomics), allowing key insights into the function and mechanism of small to very large biomolecules on a molecular level. This Feature highlights the recent advances in molecular omics focusing on miniaturized LC technology combined with mass spectrometry-based platforms, with a particular emphasis on the strategies adopted and applications using new and sensitive nanoscale analytical methodologies.

Keywords

performance liquid-chromatography; monolithic stationary phases; ionization-mass-spectrometry; nano-lc; flow chromatography; capillary columns; rosemary extract; microfluidic lc; separation; proteomics

Authors

AYDOFAN, C.; RIGANO, F.; KUJOVSKÁ KRČMOVÁ, L.; CHUNG, DS.; MACKA, M.; MONDELLO, L.

Released

1. 9. 2020

ISBN

0003-2700

Periodical

ANALYTICAL CHEMISTRY

Year of study

92

Number

17

State

United States of America

Pages from

11485

Pages to

11497

Pages count

13

URL

https://doi.org/10.1021/acs.analchem.0c01436

BibTex

@article{BUT169269,
  author="AYDOFAN, C. and RIGANO, F. and KUJOVSKÁ KRČMOVÁ, L. and CHUNG, DS. and MACKA, M. and MONDELLO, L.",
  title="Miniaturized LC in Molecular Omics",
  journal="ANALYTICAL CHEMISTRY",
  year="2020",
  volume="92",
  number="17",
  pages="11485--11497",
  doi="10.1021/acs.analchem.0c01436",
  issn="0003-2700",
  url="https://doi.org/10.1021/acs.analchem.0c01436"
}