Detail publikace

Miniaturized LC in Molecular Omics

AYDOFAN, C. RIGANO, F. KUJOVSKÁ KRČMOVÁ, L. CHUNG, DS. MACKA, M. MONDELLO, L.

Originální název

Miniaturized LC in Molecular Omics

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Miniaturized LC has evolved at an exponential rate over the last 50 years. In the past decade, it has received considerable attention in the field of bioanalytical separation science and technology due to the need to measure different classes of biomolecules present in a variety of matrixes on a global scale to gain a deeper understanding of complex biological processes. This field has become a dominant area underpinning the molecular omics research (e.g., proteomics, metabolomics, lipidomics, and foodomics), allowing key insights into the function and mechanism of small to very large biomolecules on a molecular level. This Feature highlights the recent advances in molecular omics focusing on miniaturized LC technology combined with mass spectrometry-based platforms, with a particular emphasis on the strategies adopted and applications using new and sensitive nanoscale analytical methodologies.

Klíčová slova

performance liquid-chromatography; monolithic stationary phases; ionization-mass-spectrometry; nano-lc; flow chromatography; capillary columns; rosemary extract; microfluidic lc; separation; proteomics

Autoři

AYDOFAN, C.; RIGANO, F.; KUJOVSKÁ KRČMOVÁ, L.; CHUNG, DS.; MACKA, M.; MONDELLO, L.

Vydáno

1. 9. 2020

ISSN

0003-2700

Periodikum

ANALYTICAL CHEMISTRY

Ročník

92

Číslo

17

Stát

Spojené státy americké

Strany od

11485

Strany do

11497

Strany počet

13

URL

https://doi.org/10.1021/acs.analchem.0c01436

BibTex

@article{BUT169269,
  author="AYDOFAN, C. and RIGANO, F. and KUJOVSKÁ KRČMOVÁ, L. and CHUNG, DS. and MACKA, M. and MONDELLO, L.",
  title="Miniaturized LC in Molecular Omics",
  journal="ANALYTICAL CHEMISTRY",
  year="2020",
  volume="92",
  number="17",
  pages="11485--11497",
  doi="10.1021/acs.analchem.0c01436",
  issn="0003-2700",
  url="https://doi.org/10.1021/acs.analchem.0c01436"
}