Publication detail

Silver Nanoparticles Stabilized with Phosphorus-Containing Heterocyclic Surfactants: Synthesis, Physico-Chemical Properties, and Biological Activity Determination

PISÁRČIK, M. LUKÁČ, M. JAMPÍLEK, J. BILKA, F. BÍLKOVÁ, A. PAŠKOVÁ, L. DEVÍNSKY, F. HORÁKOVÁ, R. BŘEZINA, M. OPRAVIL, T.

Original Title

Silver Nanoparticles Stabilized with Phosphorus-Containing Heterocyclic Surfactants: Synthesis, Physico-Chemical Properties, and Biological Activity Determination

Type

journal article in Web of Science

Language

English

Original Abstract

Phosphorus-containing heterocyclic cationic surfactants alkyldimethylphenylphospholium bromides with the alkyl chain length 14 to 18 carbon atoms were used for the stabilization of silver nanodispersions. Zeta potential of silver nanodispersions ranges from +35 to +70 mV, which indicates the formation of stable silver nanoparticles (AgNPs). Long-chain heptadecyl and octadecyl homologs of the surfactants series provided the most intensive stabilizing effect to AgNPs, resulting in high positive zeta potential values and smaller diameter of AgNPs in the range 50-60 nm. A comparison with non-heterocyclic alkyltrimethylphosphonium surfactants of the same alkyl chain length showed better stability and more positive zeta potential values for silver nanodispersions stabilized with heterocyclic phospholium surfactants. Investigations of biological activity of phospholium-capped AgNPs are represented by the studies of antimicrobial activity and cytotoxicity. While cytotoxicity results revealed an increased level of HepG2 cell growth inhibition as compared with the cytotoxicity level of silver-free surfactant solutions, no enhanced antimicrobial action of phospholium-capped AgNPs against microbial pathogens was observed. The comparison of cytotoxicity of AgNPs stabilized with various non-heterocyclic ammonium and phosphonium surfactants shows that AgNPs capped with heterocyclic alkyldimethylphenylphospholium and non-heterocyclic triphenyl-substituted phosphonium surfactants have the highest cytotoxicity among silver nanodispersions stabilized by the series of ammonium and phosphonium surfactants.

Keywords

phosphonium; silver nanoparticles; dynamic light scattering; zeta potential; Hep G2 cells; cytotoxicity

Authors

PISÁRČIK, M.; LUKÁČ, M.; JAMPÍLEK, J.; BILKA, F.; BÍLKOVÁ, A.; PAŠKOVÁ, L.; DEVÍNSKY, F.; HORÁKOVÁ, R.; BŘEZINA, M.; OPRAVIL, T.

Released

22. 7. 2021

Publisher

MDPI

Location

BASEL

ISBN

2079-4991

Periodical

Nanomaterials

Year of study

11

Number

8

State

Swiss Confederation

Pages from

1

Pages to

17

Pages count

17

URL

https://www.mdpi.com/2079-4991/11/8/1883

Full text in the Digital Library

http://hdl.handle.net/11012/204055

BibTex

@article{BUT176266,
  author="Martin {Pisárčik} and Miloš {Lukáč} and Josef {Jampílek} and František {Bilka} and Andrea {Bílková} and Ludmila {Pašková} and Ferdinand {Devínsky} and Renata {Horáková} and Matěj {Březina} and Tomáš {Opravil}",
  title="Silver Nanoparticles Stabilized with Phosphorus-Containing Heterocyclic Surfactants: Synthesis, Physico-Chemical Properties, and Biological Activity Determination",
  journal="Nanomaterials",
  year="2021",
  volume="11",
  number="8",
  pages="1--17",
  doi="10.3390/nano11081883",
  issn="2079-4991",
  url="https://www.mdpi.com/2079-4991/11/8/1883"
}