Detail publikace

Silver Nanoparticles Stabilized with Phosphorus-Containing Heterocyclic Surfactants: Synthesis, Physico-Chemical Properties, and Biological Activity Determination

PISÁRČIK, M. LUKÁČ, M. JAMPÍLEK, J. BILKA, F. BÍLKOVÁ, A. PAŠKOVÁ, L. DEVÍNSKY, F. HORÁKOVÁ, R. BŘEZINA, M. OPRAVIL, T.

Originální název

Silver Nanoparticles Stabilized with Phosphorus-Containing Heterocyclic Surfactants: Synthesis, Physico-Chemical Properties, and Biological Activity Determination

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Phosphorus-containing heterocyclic cationic surfactants alkyldimethylphenylphospholium bromides with the alkyl chain length 14 to 18 carbon atoms were used for the stabilization of silver nanodispersions. Zeta potential of silver nanodispersions ranges from +35 to +70 mV, which indicates the formation of stable silver nanoparticles (AgNPs). Long-chain heptadecyl and octadecyl homologs of the surfactants series provided the most intensive stabilizing effect to AgNPs, resulting in high positive zeta potential values and smaller diameter of AgNPs in the range 50-60 nm. A comparison with non-heterocyclic alkyltrimethylphosphonium surfactants of the same alkyl chain length showed better stability and more positive zeta potential values for silver nanodispersions stabilized with heterocyclic phospholium surfactants. Investigations of biological activity of phospholium-capped AgNPs are represented by the studies of antimicrobial activity and cytotoxicity. While cytotoxicity results revealed an increased level of HepG2 cell growth inhibition as compared with the cytotoxicity level of silver-free surfactant solutions, no enhanced antimicrobial action of phospholium-capped AgNPs against microbial pathogens was observed. The comparison of cytotoxicity of AgNPs stabilized with various non-heterocyclic ammonium and phosphonium surfactants shows that AgNPs capped with heterocyclic alkyldimethylphenylphospholium and non-heterocyclic triphenyl-substituted phosphonium surfactants have the highest cytotoxicity among silver nanodispersions stabilized by the series of ammonium and phosphonium surfactants.

Klíčová slova

phosphonium; silver nanoparticles; dynamic light scattering; zeta potential; Hep G2 cells; cytotoxicity

Autoři

PISÁRČIK, M.; LUKÁČ, M.; JAMPÍLEK, J.; BILKA, F.; BÍLKOVÁ, A.; PAŠKOVÁ, L.; DEVÍNSKY, F.; HORÁKOVÁ, R.; BŘEZINA, M.; OPRAVIL, T.

Vydáno

22. 7. 2021

Nakladatel

MDPI

Místo

BASEL

ISSN

2079-4991

Periodikum

Nanomaterials

Ročník

11

Číslo

8

Stát

Švýcarská konfederace

Strany od

1

Strany do

17

Strany počet

17

URL

https://www.mdpi.com/2079-4991/11/8/1883

Plný text v Digitální knihovně

http://hdl.handle.net/11012/204055

BibTex

@article{BUT176266,
  author="Martin {Pisárčik} and Miloš {Lukáč} and Josef {Jampílek} and František {Bilka} and Andrea {Bílková} and Ludmila {Pašková} and Ferdinand {Devínsky} and Renata {Horáková} and Matěj {Březina} and Tomáš {Opravil}",
  title="Silver Nanoparticles Stabilized with Phosphorus-Containing Heterocyclic Surfactants: Synthesis, Physico-Chemical Properties, and Biological Activity Determination",
  journal="Nanomaterials",
  year="2021",
  volume="11",
  number="8",
  pages="1--17",
  doi="10.3390/nano11081883",
  issn="2079-4991",
  url="https://www.mdpi.com/2079-4991/11/8/1883"
}