Přístupnostní navigace
E-přihláška
Vyhledávání Vyhledat Zavřít
Detail projektu
Období řešení: 01.01.2020 — 31.12.2022
Zdroje financování
Grantová agentura České republiky - Juniorské granty
- plně financující
O projektu
The project focuses on the solution of a complex system of separation of protein samples and subsequent scanning of electroanalytical signals in microfluidic configurations using optimized microelectrode fields (MEAs). The combination of MEAs with electronic lock-in amplifiers allows very rapid protein analysis with low detection limits using new types of pulse methods while maintaining reproducibility comparable to laboratory potentiostats. Protein-like intracellular and free-flowing proteins work as potential markers for a variety of diseases. Their separation from blood samples will bring progress in the possibility of early detection of, e.g., cancer. The separation of blood samples and the use of MEAs on the chip itself is up to date in protein assays, as they eliminate some of the disadvantages of standard electrode systems, such as low achievable rate determination of large numbers of samples and insufficient detection limits. This portable chip can then be configured for a wide range of Lab-On-Chip applications.
Klíčová slovamicroelectrode array:lab-on-chip;microfluidic chip;biosensor;lock-in amplifier;glutathione
Označení
20-30129Y
Originální jazyk
angličtina
Řešitelé
Hrdý Radim, Ing., Ph.D. - hlavní řešitel
Útvary
Chytré nanonástroje- příjemce (01.01.2020 - 31.12.2022)
Výsledky
EHLICH, J.; MIGLIACCIO, L.; SAHALIANOV, I.; NIKIĆ, M.; BRODSKÝ, J.; GABLECH, I.; VU, X.; INGEBRANDT, S.; GLOWACKI, E. Direct measurement of oxygen reduction reactions at neurostimulation electrodes. Journal of Neural Engineering, 2022, vol. 19, no. 3, p. 036045 ( p.)ISSN: 1741-2552.Detail
MIDLIK, S.; GABLECH, I.; GOLEŇA, M.; BRODSKÝ, J.; SCHMORANZER, D. Parylene-bonded micro-fluidic channels for cryogenic experiments at superfluid He-4 temperatures. Review of Scientific Instruments, 2024, vol. 95, no. 3, ISSN: 0034-6748.Detail
GABLECH, I.; MIGLIACCIO, L.; BRODSKÝ, J.; HAVLÍČEK, M.; PODEŠVA, P.; HRDÝ, R.; EHLICH, J.; GRYSZEL, M.; GLOWACKI, E. High-Conductivity Stoichiometric Titanium Nitride for Bioelectronics. Advanced Electronic Materials, 2023, vol. 9, no. 4, p. 1-11. ISSN: 2199-160X.Detail