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HYNEK, D. TMEJOVÁ, K. TRNKOVÁ, L. HUBÁLEK, J. ADAM, V. KIZEK, R.
Originální název
Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction
Typ
kapitola v knize
Jazyk
angličtina
Originální abstrakt
Application of electrochemical methods for protein determination was discovered in the thirties of the last century. Rudolf Brdicka was one who focused his attention to the protein electrochemical determination and used discovered analytical method for clinical purposes. Brdicka way of protein detection was based on the specific reaction between thiol group of proteins with Brdicka solution. Metallothionein (MT) as a low-molecular mass protein with high thiols content seems to be ideal target for such detection. This protein is involved in heavy metals homeostasis due to their chelation centers in MT structure.
Klíčová slova
metallothionein, Brdicka reaction, thiol compound, mercury electrode, tumour diseases, automation
Autoři
HYNEK, D.; TMEJOVÁ, K.; TRNKOVÁ, L.; HUBÁLEK, J.; ADAM, V.; KIZEK, R.
Rok RIV
2013
Vydáno
1. 6. 2013
Nakladatel
Nova Science Publisher, Inc.
ISBN
978-1-62948-057-2
Kniha
Voltammetry: Theory, Types and Applications
Číslo edice
1
Strany od
Strany do
12
Strany počet
URL
http://web2.mendelu.cz/af_239_nanotech/data/pub/Kizek%20from%20978-1-62948-057-2.pdf
BibTex
@inbook{BUT101248, author="David {Hynek} and Kateřina {Tmejová} and Libuše {Trnková} and Jaromír {Hubálek} and Vojtěch {Adam} and René {Kizek}", title="Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction", booktitle="Voltammetry: Theory, Types and Applications", year="2013", publisher="Nova Science Publisher, Inc.", edition="1", pages="1--12", isbn="978-1-62948-057-2", url="http://web2.mendelu.cz/af_239_nanotech/data/pub/Kizek%20from%20978-1-62948-057-2.pdf" }