Detail publikace

Nanoparticles formed by self-assembly of negatively charged hyaluronan and cationic surfactant

PILGROVÁ, T. PEKAŘ, M. HEJNÁ, J.

Originální název

Nanoparticles formed by self-assembly of negatively charged hyaluronan and cationic surfactant

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

Physico-chemical interactions in hyaluronan-surfactant system result in nanoparticles formation which can be used in targeted delivery of hydrophobic active substances. The aim of our study was to prepare hyaluronic acid nanoparticles based on electrostatic interactions with oppositely charged molecules. Particles were investigated using dynamic light scattering and Laser Doppler Velocimetry methods. Size distribution and zeta potential measurement were utilized to explore the formation of complex micelles. Particles size distributions depend on type of solvent, molecular weight of hyaluronan and charge ratio of components of the hyaluronan-surfactant system. Aggregates formation is influenced by preparation of the system. Stability of the micellar particles depends on zeta potential value.

Klíčová slova

hyaluronan, surfactant, nanoparticles, dynamic light scattering, size distribution, zeta potential

Autoři

PILGROVÁ, T.; PEKAŘ, M.; HEJNÁ, J.

Rok RIV

2013

Vydáno

16. 10. 2013

Nakladatel

TANGER, Ltd., Keltickova 62, 710 00 Ostrava, Czech Republic, EU

Místo

Ostrava

ISBN

978-80-87294-47-5

Kniha

NANOCON 2013 Conference Proceedings

Edice

1st

Strany od

595

Strany do

599

Strany počet

6

URL

http://konsys-t.tanger.cz/files/proceedings/14/reports/1926.pdf

BibTex

@inproceedings{BUT127413,
  author="Tereza {Pilgrová} and Miloslav {Pekař} and Jana {Mourycová}",
  title="Nanoparticles formed by self-assembly of negatively charged hyaluronan and cationic surfactant",
  booktitle="NANOCON 2013 Conference Proceedings",
  year="2013",
  series="1st",
  pages="595--599",
  publisher="TANGER, Ltd., Keltickova 62, 710 00 Ostrava, Czech Republic, EU",
  address="Ostrava",
  isbn="978-80-87294-47-5",
  url="http://konsys-t.tanger.cz/files/proceedings/14/reports/1926.pdf"
}