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KARGEROVÁ, A. PEKAŘ, M.
Originální název
Ultrasonic study of hyaluronan interactions with Septonex – a pharmaceutical cationic surfactant
Typ
článek v časopise ve Web of Science, Jimp
Jazyk
angličtina
Originální abstrakt
Interactions between hyaluronan and the cationic surfactant Septonex were studied using high resolution ultrasound spectroscopy. Four different interaction regions were identified in aqueous solution in a narrow interval of surfactant concentrations. In contrast, in 0.15 mol/L NaCl solution, essentially only two principal regions were observed. Hyaluronan-Septonex aggregates were generally less compressible than Septonex monomers or micelles and their formation in water was not appreciably affected by hyaluronan molecular weight. In the presence of NaCl, the effect of hyaluronan molecular weight was more profound, which can be ascribed to its conformational sensitivity to ionic strength combined with its role as a surfactant counterion. Hyaluronan-Septonex interactions were closer to interactions with CTAB than with TTAB. Differences in structure or Krafft temperature (solubility) between Septonex and CTAB were thus not significantly reflected in these interactions. The basic characteristics of Septonex surfactant were also determined.
Klíčová slova
hyaluronan; Septonex; ultrasonic velocity; compressibility; surfactant
Autoři
KARGEROVÁ, A.; PEKAŘ, M.
Vydáno
1. 1. 2019
ISSN
0144-8617
Periodikum
Carbohydrate Polymers
Ročník
204
Číslo
1
Stát
Spojené království Velké Británie a Severního Irska
Strany od
17
Strany do
23
Strany počet
7
URL
https://doi.org/10.1016/j.carbpol.2018.09.077
BibTex
@article{BUT150480, author="Andrea {Hurčíková} and Miloslav {Pekař}", title="Ultrasonic study of hyaluronan interactions with Septonex – a pharmaceutical cationic surfactant", journal="Carbohydrate Polymers", year="2019", volume="204", number="1", pages="17--23", doi="10.1016/j.carbpol.2018.09.077", issn="0144-8617", url="https://doi.org/10.1016/j.carbpol.2018.09.077" }