Detail publikace

DEAE-dextran hydrochloride behaviour in aqueous solution—The effect of ionic strength and concentration

KALINA, M. KARGEROVÁ, A. PEKAŘ, M.

Originální název

DEAE-dextran hydrochloride behaviour in aqueous solution—The effect of ionic strength and concentration

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

DEAE-dextran hydrochloride is a positively charged biocompatible polyelectrolyte. Its behaviour in aqueous solutions – the changes in its colloidal characteristics and resulting conformation changes – were investigated using a combination of light scattering, densitometry and ultrasound spectrometry. The results indicated the formation of a voluminous, hydrated and coiled conformation of chains having average particle sizes in the range of units of microns at low ionic strength. This phenomenon was supported by an increase in DEAE-dextran hydrochloride concentration in the solution. The increase in ionic strength caused the shielding of DEAE-dextran hydrochloride charges on its chain, resulting in the destabilization of the conformation arrangement of the polyelectrolyte and the formation of denser, more compact and stiffer structures having smaller particle sizes. The proposed model of DEAE-dextran hydrochloride density in the studied environments (distilled water, NaCl solutions) showed the possibility of using a single equation model to calculate the overall density of the system.

Klíčová slova

DEAE-dextran hydrochloride; conformation; ionic strength; polyelectrolyte; density model

Autoři

KALINA, M.; KARGEROVÁ, A.; PEKAŘ, M.

Vydáno

15. 9. 2019

Nakladatel

Elsevier Ltd.

Místo

Oxford, England

ISSN

0144-8617

Periodikum

Carbohydrate Polymers

Číslo

220

Stát

Spojené království Velké Británie a Severního Irska

Strany od

163

Strany do

169

Strany počet

7

URL

https://doi.org/10.1016/j.carbpol.2019.05.070

BibTex

@article{BUT157110,
  author="Michal {Kalina} and Andrea {Hurčíková} and Miloslav {Pekař}",
  title="DEAE-dextran hydrochloride behaviour in aqueous solution—The effect of ionic strength and concentration",
  journal="Carbohydrate Polymers",
  year="2019",
  number="220",
  pages="163--169",
  doi="10.1016/j.carbpol.2019.05.070",
  issn="0144-8617",
  url="https://doi.org/10.1016/j.carbpol.2019.05.070"
}