Detail publikace

Chemical Microrobots as Self-Propelled Microbrushes against Dental Biofilm

VILLA, K. VIKTOROVÁ, J. PLUTNAR, J. RUML, T. HOANG, L. PUMERA, M.

Originální název

Chemical Microrobots as Self-Propelled Microbrushes against Dental Biofilm

Typ

článek v časopise - ostatní, Jost

Jazyk

angličtina

Originální abstrakt

Mouths offer the perfect environments for microbial cell formation, promoting the growth of biofilms, for example, on teeth. Dental biofilm exhibits strong resistance to antibiotics and is a cause of many dental diseases. Common strategies for dental biofilm removal involve the addition of high concentrations of hydrogen peroxide (H2O2), which increases tooth sensitivity, or mechanical procedures. Here, we report a different approach based on self-propelled micromachines with high antibacterial activity for the degradation of dental biofilm. Such microrobots use low concentrations of fuel for their propulsion, and they achieve an efficient dental biofilm disruption in only 5 min of treatment. Moreover, these microrobots are biocompatible with epidermal and organ cells and may stimulate the immune system to fight against microbial infection. This approach of exploiting the active motion of bubble-propelled catalytic micromachines for oral biofilm disruption may open the door for more efficient and sophisticated treatments in dentistry.

Klíčová slova

micromotors;bubble propulsion;hydroxyl radicals;dental biofilm;titanium dioxide;antibacterial activity;biofilm disruption;gum treatment

Autoři

VILLA, K.; VIKTOROVÁ, J.; PLUTNAR, J.; RUML, T.; HOANG, L.; PUMERA, M.

Vydáno

23. 9. 2020

Nakladatel

Cell Press

ISSN

2666-3864

Periodikum

Cell Reports Physical Science

Ročník

1

Číslo

9

Stát

Spojené státy americké

Strany od

1

Strany do

18

Strany počet

18

URL

https://www.sciencedirect.com/science/article/pii/S2666386420301922

Plný text v Digitální knihovně

http://hdl.handle.net/11012/195857

BibTex

@article{BUT167681,
  author="Katherine {Villa} and Jitka {Viktorová} and Jan {Plutnar} and Tomáš {Ruml} and Lan {Hoang} and Martin {Pumera}",
  title="Chemical Microrobots as Self-Propelled Microbrushes against Dental Biofilm",
  journal="Cell Reports Physical Science",
  year="2020",
  volume="1",
  number="9",
  pages="1--18",
  doi="10.1016/j.xcrp.2020.100181",
  issn="2666-3864",
  url="https://www.sciencedirect.com/science/article/pii/S2666386420301922"
}