Detail publikace

TNF-alpha can induce lymphocyte apoptosis during experimentally induced mastitis caused by lipopolysaccharide

SLÁMA, P. KABOURKOVÁ, E. PAVLÍK, A.

Originální název

TNF-alpha can induce lymphocyte apoptosis during experimentally induced mastitis caused by lipopolysaccharide

Typ

abstrakt

Jazyk

angličtina

Originální abstrakt

The aim of this study was to determine whether lymphocyte apoptosis is modulated by infections caused by Staphylococcus aureus and Streptococcus uberis. Samples of cell populations were obtained by lavage of the mammary glands at 4 intervals (24,48, 72 and 168 h) following infection. The percentage of apoptotic lymphocytes peaked at 168 h after challenge with S. aureus or S. uberis. Subsequent experiments focused on in vitro cultivation of mammary gland lymphocytes with S. aureus and S. uberis. These experiments showed a lower percentage of apoptotic lymphocytes following 3 h of cultivating cells with bacteria than after cultivation without bacteria. The results demonstrate that during both experimental infection of bovine mammary glands with S. aureus or S. uberis and during in vitro cultivation of lymphocytes with S. aureus or S. uberis, apoptosis of lymphocytes is delayed

Klíčová slova

STIMULATION

Autoři

SLÁMA, P.; KABOURKOVÁ, E.; PAVLÍK, A.

Vydáno

17. 10. 2017

ISSN

1365-3083

Periodikum

Scandinavian Journal of Immunology

Ročník

86

Číslo

4

Stát

Spojené království Velké Británie a Severního Irska

Strany od

286

Strany do

286

Strany počet

1

BibTex

@misc{BUT170242,
  author="Petr {Sláma} and Eliška {Kabourková} and Aleš {Pavlík}",
  title="TNF-alpha can induce lymphocyte apoptosis during experimentally induced mastitis caused by lipopolysaccharide",
  year="2017",
  journal="Scandinavian Journal of Immunology",
  volume="86",
  number="4",
  pages="286--286",
  issn="1365-3083",
  note="abstract"
}