Detail publikace

Invasive Electrophysiology for Circuit Discovery and Study of Comorbid Psychiatric Disorders in Patients With Epilepsy: Challenges, Opportunities, and Novel Technologies

BALZEKAS, I. SLADKÝ, V. NEJEDLÝ, P. BRINKMANN, B. CREPEAU, D. MÍVALT, F. GREGG, N. ATTIA, T. MARKS, V. WHEELER, L. RICELLI, T. STAAB, J. LUNDSTROM, B. MILLER, K. VAN GOMPEL, J. KŘEMEN, V. CROARKIN, P. WORRELL, G.

Originální název

Invasive Electrophysiology for Circuit Discovery and Study of Comorbid Psychiatric Disorders in Patients With Epilepsy: Challenges, Opportunities, and Novel Technologies

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Intracranial electroencephalographic (iEEG) recordings from patients with epilepsy provide distinct opportunities and novel data for the study of co-occurring psychiatric disorders. Comorbid psychiatric disorders are very common in drug-resistant epilepsy and their added complexity warrants careful consideration. In this review, we first discuss psychiatric comorbidities and symptoms in patients with epilepsy. We describe how epilepsy can potentially impact patient presentation and how these factors can be addressed in the experimental designs of studies focused on the electrophysiologic correlates of mood. Second, we review emerging technologies to integrate long-term iEEG recording with dense behavioral tracking in naturalistic environments. Third, we explore questions on how best to address the intersection between epilepsy and psychiatric comorbidities. Advances in ambulatory iEEG and long-term behavioral monitoring technologies will be instrumental in studying the intersection of seizures, epilepsy, psychiatric comorbidities, and their underlying circuitry.

Klíčová slova

epilepsy; psychiatric disorders; major depression (MDD); SEEG (stereoelectroencephalography); electrocorticography (ECoG); deep brain stimulation; biomarker; neuromodulation

Autoři

BALZEKAS, I.; SLADKÝ, V.; NEJEDLÝ, P.; BRINKMANN, B.; CREPEAU, D.; MÍVALT, F.; GREGG, N.; ATTIA, T.; MARKS, V.; WHEELER, L.; RICELLI, T.; STAAB, J.; LUNDSTROM, B.; MILLER, K.; VAN GOMPEL, J.; KŘEMEN, V.; CROARKIN, P.; WORRELL, G.

Vydáno

26. 7. 2021

Nakladatel

Frontiers Media

Místo

LAUSANNE

ISSN

1662-5161

Periodikum

Frontiers in Human Neuroscience

Ročník

15

Číslo

1

Stát

Švýcarská konfederace

Strany od

1

Strany do

17

Strany počet

17

URL

https://www.frontiersin.org/articles/10.3389/fnhum.2021.702605/full

Plný text v Digitální knihovně

http://hdl.handle.net/11012/203033

BibTex

@article{BUT172290,
  author="Irena {Balzekas} and Vladimír {Sladký} and Petr {Nejedlý} and Benjamin H. {Brinkmann} and Daniel {Crepeau} and Filip {Mívalt} and Nicholas M. {Gregg} and Tal Pal {Attia} and Victoria S. {Marks} and Lydia P. {Wheeler} and Tori E. {Ricelli} and Jeffrey P. {Staab} and Brian {Lundstrom} and Kai J. {Miller} and Jamie J. {Van Gompel} and Václav {Křemen} and Paul E. {Croarkin} and Gregory {Worrell}",
  title="Invasive Electrophysiology for Circuit Discovery and Study of Comorbid Psychiatric Disorders in Patients With Epilepsy: Challenges, Opportunities, and Novel Technologies",
  journal="Frontiers in Human Neuroscience",
  year="2021",
  volume="15",
  number="1",
  pages="1--17",
  doi="10.3389/fnhum.2021.702605",
  issn="1662-5161",
  url="https://www.frontiersin.org/articles/10.3389/fnhum.2021.702605/full"
}