Detail publikace

In Vivo Organic Bioelectronics for Neuromodulation

BERGGREN, M. GLOWACKI, E. SIMON, D. STAVRINIDIOU, E. TYBRANDT, K.

Originální název

In Vivo Organic Bioelectronics for Neuromodulation

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

The nervous system poses a grand challenge for integration with modern electronics and the subsequent advances in neurobiology, neuroprosthetics, and therapy which would become possible upon such integration. Due to its extreme complexity, multifaceted signaling pathways, and similar to 1 kHz operating frequency, modern complementary metal oxide semiconductor (CMOS) based electronics appear to be the only technology platform at hand for such integration. However, conventional CMOS-based electronics rely exclusively on electronic signaling and therefore require an additional technology platform to translate electronic signals into the language of neurobiology. Organic electronics are just such a technology platform, capable of converting electronic addressing into a variety of signals matching the endogenous signaling of the nervous system while simultaneously possessing favorable material similarities with nervous tissue. In this review, we introduce a variety of organic material platforms and signaling modalities specifically designed for this role as "translator" , focusing especially on recent implementation in in vivo neuromodulation. We hope that this review serves both as an informational resource and as an encouragement and challenge to the field.

Klíčová slova

conductive polymer; neurite out growth; electrical-stimulation; polypyrrole; tissue; electrodes; delivery; release; reduction; oxygen

Autoři

BERGGREN, M.; GLOWACKI, E.; SIMON, D.; STAVRINIDIOU, E.; TYBRANDT, K.

Vydáno

23. 2. 2022

Nakladatel

American Chemical Society

Místo

WASHINGTON

ISSN

0009-2665

Periodikum

Chemical Reviews

Ročník

122

Číslo

4

Stát

Spojené státy americké

Strany od

4826

Strany do

4846

Strany počet

21

URL

https://pubs.acs.org/doi/10.1021/acs.chemrev.1c00390

Plný text v Digitální knihovně

http://hdl.handle.net/11012/208225

BibTex

@article{BUT176412,
  author="Magnus {Berggren} and Eric Daniel {Glowacki} and Daniel T. {Simon} and Eleni {Stavrinidiou} and Klas {Tybrandt}",
  title="In Vivo Organic Bioelectronics for Neuromodulation",
  journal="Chemical Reviews",
  year="2022",
  volume="122",
  number="4",
  pages="4826--4846",
  doi="10.1021/acs.chemrev.1c00390",
  issn="0009-2665",
  url="https://pubs.acs.org/doi/10.1021/acs.chemrev.1c00390"
}