Detail publikace

Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis

PANOVSKÝ, R. DOUBKOVÁ, M. LUZ MOJICA-PISCIOTTI, M. HOLEČEK, T. MÁCHAL, J. FEITOVÁ, V. MASÁROVÁ, L. OPATŘIL, L. KINCL, V. VÍŠKOVÁ, J.

Originální název

Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Background Sarcoidosis is a systemic granulomatous disease affecting different organs including the heart. Myocardial strain analysis could potentially detect the early stages of cardiac dysfunction in sarcoidosis patients. The present study aims to assess the use of cardiac magnetic resonance (CMR) strain analysis using feature tracking (FT) in the detection of early cardiac involvement in asymptomatic patients with sarcoidosis. Methods One hundred and thirteen CMR studies of patients with sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis without pre-existing known cardiovascular disease were included in the study and analysed using FT and compared to 22 age and gender-matched controls. Global longitudinal strain (GLS), global circumferential strain (GCS) and global radial strain (GRS) of the left ventricle (LV) were measured. Results The sarcoidosis patients did not significantly differ from the controls in basic demographic data and had normal global and regional systolic LV function-LV ejection fraction (EF) 66 +/- 7% vs 65 +/- 5% in the controls (p = NS). No statistically significant differences were found in all strain parameters between patients and controls: GLS (- 13.9 +/- 3.1 vs. - 14.2 +/- 2.5), GCS (- 23.4 +/- 4.0 vs. - 22.2 +/- 2.9) and GRS (53.4 +/- 13.5 vs. 51.2 +/- 13.6%) (p = NS). Conclusion Patients with sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis had normal myocardial deformation measured by CMR-FT derived global strain

Klíčová slova

Cardiac magnetic resonance; Sarcoidosis; Feature tracking; Strain analysis

Autoři

PANOVSKÝ, R.; DOUBKOVÁ, M.; LUZ MOJICA-PISCIOTTI, M.; HOLEČEK, T.; MÁCHAL, J.; FEITOVÁ, V.; MASÁROVÁ, L.; OPATŘIL, L.; KINCL, V.; VÍŠKOVÁ, J.

Vydáno

29. 9. 2021

Nakladatel

BMC

Místo

LONDON

ISSN

1750-1172

Periodikum

Orphanet Journal of Rare Diseases

Ročník

16

Číslo

1

Stát

Spojené království Velké Británie a Severního Irska

Strany od

1

Strany do

8

Strany počet

8

URL

https://ojrd.biomedcentral.com/articles/10.1186/s13023-021-02038-2

BibTex

@article{BUT178951,
  author="Roman {Panovský} and Martina {Doubková} and Mary {Luz Mojica-Pisciotti} and Tomáš {Holeček} and Jan {Máchal} and Věra {Feitová} and Lucia {Masárová} and Lukáš {Opatřil} and Vladimír {Kincl} and Jana {Víšková}",
  title="Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis",
  journal="Orphanet Journal of Rare Diseases",
  year="2021",
  volume="16",
  number="1",
  pages="1--8",
  doi="10.1186/s13023-021-02038-2",
  issn="1750-1172",
  url="https://ojrd.biomedcentral.com/articles/10.1186/s13023-021-02038-2"
}