Detail publikace

Microfluidic trends in drug screening and drug delivery

Jianguo Feng, Jiri Neuzil, Andreas manz, Ciprian Iliescu, Pavel Neuzil

Originální název

Microfluidic trends in drug screening and drug delivery

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

The low probability of a drug candidate's clinical success, the time consumed and the high cost of bringing a drug from concept to market emphasizes the need for new approaches to drug discovery. Recent innovations in microfluidic technologies, including organ-on-a-chip, droplet microfluidics and high-throughput screening are revealing the potential of these platforms to address some of these challenges, due to the small volume of samples consumed, short processing time, and improved process control. Here, we review selected recent progress in the development and application of microfluidic technologies in drug screening and drug delivery, highlighting the trends and associated challenges.

Klíčová slova

Microfluidic technologies; Drug screeningDrug delivery; Drug discovery

Autoři

Jianguo Feng, Jiri Neuzil, Andreas manz, Ciprian Iliescu, Pavel Neuzil

Vydáno

1. 1. 2023

Nakladatel

Elsevier

Místo

Netherlands

ISSN

0165-9936

Periodikum

TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Ročník

158

Číslo

116821

Stát

Spojené království Velké Británie a Severního Irska

Strany počet

18

URL

https://www.sciencedirect.com/science/article/abs/pii/S0956566323002610?via%3Dihub

BibTex

@article{BUT183689,
  author="Pavel {Neužil}",
  title="Microfluidic trends in drug screening and drug delivery
",
  journal="TRAC-TRENDS IN ANALYTICAL CHEMISTRY",
  year="2023",
  volume="158",
  number="116821",
  pages="18",
  doi="10.1016/j.trac.2022.116821",
  issn="0165-9936",
  url="https://www.sciencedirect.com/science/article/abs/pii/S0956566323002610?via%3Dihub"
}