Detail publikace

Interictal invasive very high-frequency oscillations in resting awake state and sleep

TRÁVNÍČEK, V. REVAJOVÁ, K. HALÁMEK, J. PAIL, M.

Originální název

Interictal invasive very high-frequency oscillations in resting awake state and sleep

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Interictal very high-frequency oscillations (VHFOs, 500-2000 Hz) in a resting awake state seem to be, according to a precedent study of our team, a more specific predictor of a good outcome of the epilepsy surgery compared to traditional interictal high-frequency oscillations (HFOs, 80-500 Hz). In this study, we retested this hypothesis on a larger cohort of patients. In addition, we also collected patients' sleep data and hypothesized that the occurrence of VHFOs in sleep will be greater than in resting state. We recorded interictal invasive electroencephalographic (iEEG) oscillations in 104 patients with drug-resistant epilepsy in a resting state and in 35 patients during sleep. 21 patients in the rest study and 11 patients in the sleep study met the inclusion criteria (interictal HFOs and VHFOs present in iEEG recordings, a surgical intervention and a postoperative follow-up of at least 1 year) for further evaluation of iEEG data. In the rest study, patients with good postoperative outcomes had significantly higher ratio of resected contacts with VHFOs compared to HFOs. In sleep, VHFOs were more abundant than in rest and the percentage of resected contacts in patients with good and poor outcomes did not considerably differ in any type of oscillations. In conclusion, (1) our results confirm, in a larger patient cohort, our previous work about VHFOs being a specific predictor of the area which needs to be resected; and (2) that more frequent sleep VHFOs do not further improve the results.

Klíčová slova

epilepsy, very high frequency oscillations, EEG

Autoři

TRÁVNÍČEK, V.; REVAJOVÁ, K.; HALÁMEK, J.; PAIL, M.

Vydáno

6. 11. 2023

Nakladatel

NATURE PORTFOLIO

Místo

BERLIN

ISSN

2045-2322

Periodikum

Scientific Reports

Ročník

13

Číslo

19225

Stát

Spojené království Velké Británie a Severního Irska

Strany počet

11

URL

http://www.nature.com/articles/s41598-023-46024-z

BibTex

@article{BUT189984,
  author="Vojtěch {Trávníček} and Karin {Revajová} and Josef {Halámek} and Martin {Pail}",
  title="Interictal invasive very high-frequency oscillations in resting awake state and sleep",
  journal="Scientific Reports",
  year="2023",
  volume="13",
  number="19225",
  pages="11",
  doi="10.1038/s41598-023-46024-z",
  issn="2045-2322",
  url="http://www.nature.com/articles/s41598-023-46024-z"
}