Detail publikace

Exploring Speech Profiles in Parkinson's Disease Patients on Long - Term Dopaminergic Medication

KOVÁČ, D. NOVOTNÝ, K. MEKYSKA, J. BRABENEC, L. KOŠŤÁLOVÁ, M. REKTOROVÁ, I.

Originální název

Exploring Speech Profiles in Parkinson's Disease Patients on Long - Term Dopaminergic Medication

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

Hypokinetic dysarthria (HD), prevalent in Parkin-son's disease (PD), is characterized by reduced motor movement, leading to speech and voice impairments. The effectiveness of dopamine therapy varies, and symptoms may change over time. To explore the HD in patients on medication, we conducted hierarchical clustering to categorize 83 PD patients using the acoustic features extracted from recorded text reading, sustained phonation, and diadochokinetic task. We then compared these clusters to a group of 44 healthy controls. Regardless of the medication dosage and PD duration, patients displayed three distinct speech profiles: articulatory; respiratory-prosodic; and another more complex/severe regarding the number of HD do-mains affected. The newly identified profiles exhibit distinctions from previously defined speech subtypes in de novo PD patients. No differences in clinical scores were observed among the newly identified profiles, suggesting uniformity in clinical presentation despite distinct speech characteristics.

Klíčová slova

Acoustic Analysis; Clustering; Dopamine Therapy; Hypokinetic Dysarthria, Parkinson’s Disease, Speech Profiles

Autoři

KOVÁČ, D.; NOVOTNÝ, K.; MEKYSKA, J.; BRABENEC, L.; KOŠŤÁLOVÁ, M.; REKTOROVÁ, I.

Vydáno

30. 7. 2024

Nakladatel

IEEE

ISBN

979-8-3503-6559-7

Kniha

2024 47th International Conference on Telecommunications and Signal Processing (TSP)

Strany od

270

Strany do

273

Strany počet

4

URL

https://doi.org/10.1109/TSP63128.2024.10605914

BibTex

@inproceedings{BUT189257,
  author="Daniel {Kováč} and Kryštof {Novotný} and Jiří {Mekyska} and Luboš {Brabenec} and Milena {Košťálová} and Irena {Rektorová}",
  title="Exploring Speech Profiles in Parkinson's Disease Patients on Long - Term Dopaminergic Medication",
  booktitle="2024 47th International Conference on Telecommunications and Signal Processing (TSP)",
  year="2024",
  pages="270--273",
  publisher="IEEE",
  doi="10.1109/TSP63128.2024.10605914",
  isbn="979-8-3503-6559-7",
  url="https://doi.org/10.1109/TSP63128.2024.10605914"
}